A Sinister Bacteria: Vibrio Cholerae

  An internationally-known disease is usually not a good concept when it comes to world-wide health centers; often because the terrible, lethal illness it brings. What could be the reason behind such a calamity? It’s simple, a mean little bacteria called Vibrio cholerae. According to the CDC (Centers for Disease Control and Prevention), Cholera, caused by the bacteria V. cholerae, is rare in the United States and other industrialized nations. However, globally, cholera cases have increased steadily since 2005 and the disease still occurs in many places including Africa, Southeast Asia, and Haiti.

  Looking a little deeper into this, infection due to V. cholerae begins with the ingestion of contaminated water or food. After passage through the acid barrier of the stomach, the organism colonizes the epithelium of the small intestine by means of the toxin-coregulated pili (Taylor et al., 1987). Toxin is then produced by V. cholerae and secreted into the surrounding intestinal epithelial tissue, where it disrupts ion transport. Severe diarrhea and vomiting follow, where the infected person experiences a catastrophic loss of water and electrolytes. 

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https://microbewiki.kenyon.edu/index.php/Cholera

Figure 1. V. Cholerae seen with its single, sheathed, polar flagellum.

Glancing at the bacteria itself: V. cholerae, a member of the family Vibrionaceae, is a facultatively anaero-bic, Gram-negative, non-spore-forming curved rod, about 1.4–2.6mm long, capable of respiratory and fermentative metabolism; it is well defined on the basis of biochemical tests and DNA homology studies (Baumann, Furniss & Lee, 1984). Seen in the figure above, V. cholerae has a means of motility via flagellum.

 

  • HAYDEN SWARTZ 9/22/17

 

 

 

Bibilography

Baumann P, Furniss AL, Lee JV (1984). Genus 1, Vibrio. In: Krieg PNR, Halt JG, eds. Bergey’s manual of systematic bacteriology. Vol. 1. Baltimore, Williams & Wilkins: 518–538.

Taylor RK et al. (1987). Use of phoA gene fusions to identify a pilus coloniza- tion factor co-ordinately regulated with cholera toxin. Proceedings of the National Academy of Sciences, 84:2833–2837.

3 thoughts on “A Sinister Bacteria: Vibrio Cholerae

  1. You have so much good information but you should take another pass through for grammar and sentence structure. For example, there are a lot of unnecessary commas all throughout your post; “An internationally known disease (NO COMMA)…”. I would recommend rewriting the first sentence in your second paragraph to get rid of the phrase in parenthesis and also the first sentence in the first paragraph just for clarity. The citation for your image should be immediately underneath rather than in the post. You can do that by adding a “caption” to the image. It will make it appear cleaner in your overall post and clearer for the reader.

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  2. I like how you went into the specifics of how this microbe works and why it’s dangerous. Lots of interesting details! However picture could be formatted better. Overall great job!

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  3. This is a very intereting disease and you have touched on how ingestion of contaminated food results to the infection. I am looking forward to your next blog post where you might start talking about contaminated hands, improper sewage etc would also contribute its causation. It is a great start and I am looking forward to learning new stuffs about the virus and the infection.

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